OUR PIPELINE

 
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We are developing small-molecule medicines, with clinically validated mechanisms of action, to address oncology and metabolic diseases with large unmet medical need.

MECHANISM PROGRAM INDICATION PRECLINICAL STATUS EARLY STAGE CLINICAL DEVELOPMENT LATE STAGE CLINICAL DEVELOPMENT Ph 1 CARDINAL Trial initiated TERN-701 CML TERN-800 Series Allosteric BCR- ABL Inhibitor GIPR Modulators Obesity A n ti c i pa t e d r e g i s t r a ti o n a l t r i a l f o ll o w i n g P h 1 t r i al TERN-601 Obesity Oral GLP-1R Agonist Metabolic Oncology Obesity TERN-501 Combination THR- Agonist PHASE 1 Interim data from initial cohorts in 2H24 Lead optimization underway Candidate nomination & IND-enabling activities ongoing Phase 1 initiated Top-line data (28-day PoC) 2H24 Preclinical activities underway PHASE 1 Preclinical Lead optimization Metabolic Agent

1. Out-licensed to Hansoh Pharma (HS 10382) in the Greater China region; Ph1 trial ongoing in China; Terns eligible for up to $67M in clinical, regulatory and sales-based milestones, mid single digit percentage royalties on set sales; Certain milestones are subject to the availability of additional data and future funding.